What is estradiol?
Estradiol is responsible for the regulation of female menstrual reproductive cycles and for the development and maintenance of female secondary sex characteristics [.
Why is it measured?
Analysis of Estradiol levels is perfect for a variety of uses in men, such as:
- Testosterone Conversion: Since estradiol is converted from testosterone, unusually high or low levels of estradiol can indicate a problem with testosterone levels or the conversion process.
- Bone Health: Just like in women, estradiol is important for bone health in men. Monitoring estradiol levels can help assess the risk of osteoporosis in men.
- Gynecomastia: Elevated levels of estradiol in men can lead to the development of breast tissue (gynecomastia). Measuring estradiol can help diagnose the cause of this condition.
- Sexual Function and Libido: Estradiol is involved in modulating libido and erectile function in men. Unusual levels can be associated with sexual dysfunctions.
In women, it is used for:
- Menstrual Cycle Regulation: Estradiol levels vary throughout the menstrual cycle and are a key factor in regulating it. Monitoring these levels can help in understanding if the cycle is normal.
- Fertility and Ovulation: In women who are trying to conceive, measuring estradiol levels can help determine whether the ovaries are producing eggs properly.
- Hormone Replacement Therapy (HRT): Women who are undergoing HRT, especially around the time of menopause, may have their estradiol levels monitored to ensure that they are receiving the appropriate dose of hormones.
- Polycystic Ovary Syndrome (PCOS): Women with PCOS may have elevated levels of estradiol. Monitoring these levels can be part of the diagnostic process.
How can I better understand my results?
Normally Menstruating Females:
- Early Follicular Phase: 22-115 pg/mL
- Mid-Follicular Phase: 25-115 pg/mL
- Mid-Luteal Phase: 37-246 pg/mL
- Peri-Ovulatory Phase: 32-517 pg/mL
Post-Menopausal Females (not on HRT)
- <15-25 pg/mL
Males:
- 10 to 50 pg/mL for men.
Where can I learn more?
For a scientific explanation of estradiol, read here.
DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT YOUR PROVIDER