What is ApoB?
ApoB (apolipoprotein B) is an atherogenic (forms plaques in arteries) particle that transports “bad” cholesterol. Each particle of VLDL, IDL, LDL, or Lp(a) contains a single molecule of ApoB. Studies have shown that ApoB is a better predictor of cardiovascular events such as myocardial infarction than LDL in both men and women, independent of age.
Why is it included in the Cardiovascular Axis?
Because there is only one ApoB per LDL, this measurement gives us the most accurate estimate of the LDL or “bad cholesterol” in the body. ApoB is a measure of non-HDL cholesterol relative to total cholesterol. High ApoB levels are strongly associated with increased risk for cardiovascular events and shortened lifespan.
How can I better understand my results?
To better interpret your results, here are a few values that can be used to gauge your cardiovascular health. It is important to consult with your physician if you are concerned with any of your results.
High ApoB results may be indicative of pregnancy, high cholesterol, or kidney issues. Low ApoB on the other hand may be indicative of sepsis, liver disease, malabsorption, or high estrogen levels.
If your ApoB levels are higher than normal, you can try:
- 30 minutes of exercise a day
- Limiting saturated fats
- Avoiding tobacco
- Maintaining a healthy weight
- Limiting trans fat intake
- Consuming omega-3s (cold-water fish, walnuts, etc.), psyllium, and/or phytosterols (nuts, whole grains, etc.)
- Following a Mediterranean diet
Where can I learn more?
Peter Attia (podcast) – Dr. Dayspring: Lipid metrics, measurements, cholesterol regulation
NIH – Opening a New Lipid “Apo-thecary”
Cleveland Clinic – ApoB Test
DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT WITH YOUR PHYSICIAN.